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Detection of glycosaminoglycan loss in articular cartilage by fluorescence lifetime imaging

Glycosaminoglycan (GAG) loss is an early marker of osteoarthritis, which is a clinical late stage disease that affects millions of people worldwide. The goal of our study was to evaluate the ability of a fiber-based fluorescence lifetime imaging (FLIm) technique to detect GAG loss in articular carti...

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Detalles Bibliográficos
Autores principales: Zhou, Xiangnan, Haudenschild, Anne K., Sherlock, Benjamin E., Hu, Jerry C., Leach, J. Kent, Athanasiou, Kyriacos A., Marcu, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357192/
https://www.ncbi.nlm.nih.gov/pubmed/30578627
http://dx.doi.org/10.1117/1.JBO.23.12.126002