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Quantitative control of noise in mammalian gene expression by dynamic histone regulation

Fluctuation ('noise') in gene expression is critical for mammalian cellular processes. Numerous mechanisms contribute to its origins, yet the mechanisms behind large fluctuations that are induced by single transcriptional activators remain elusive. Here, we probed putative mechanisms by st...

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Detalles Bibliográficos
Autores principales: Tan, Deng, Chen, Rui, Mo, Yuejian, Gu, Shu, Ma, Jiao, Xu, Wei, Lu, Xibin, He, Huiyu, Jiang, Fan, Fan, Weimin, Wang, Yili, Chen, Xi, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357418/
https://www.ncbi.nlm.nih.gov/pubmed/34379055
http://dx.doi.org/10.7554/eLife.65654