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Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), a clinically high mortality disease, has not been effectively treated till now, and the development of anti-acute lung injury drugs is imminent. Acute lung injury was efficiently treated by inhibiting the cascade of inflammation, and...

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Detalles Bibliográficos
Autores principales: Chen, Tianpeng, Wei, Yingying, Zhu, Gaoyang, Zhao, Huajun, Zhang, Xingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357485/
https://www.ncbi.nlm.nih.gov/pubmed/34425313
http://dx.doi.org/10.1016/j.ejmech.2021.113766