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Involvement of N-Methyl-D-Aspartate Receptors in the Anticonvulsive Effects of Licofelone on Pentylenetetrazole-Induced Clonic Seizure in Mice

BACKGROUND AND PURPOSE: Licofelone is a dual 5-lipoxygenase/cyclooxygenase inhibitor, with well-documented anti-inflammatory and analgesic effects, which is used for treatment of osteoarthritis. Recent preclinical studies have also suggested neuroprotective and anti-oxidative properties of this drug...

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Detalles Bibliográficos
Autores principales: Gholizadeh, Ramtin, Abdolmaleki, Zohreh, Bahremand, Taraneh, Ghasemi, Mehdi, Gharghabi, Mehdi, Dehpour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Epilepsy Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357553/
https://www.ncbi.nlm.nih.gov/pubmed/34395219
http://dx.doi.org/10.14581/jer.21003