Cyclo-oxygenase 2, a putative mediator of vessel remodeling, is expressed in the brain AVM vessels and associates with inflammation

BACKGROUND: Brain arteriovenous malformations (bAVM) may rupture causing disability or death. BAVM vessels are characterized by abnormally high flow that in general triggers expansive vessel remodeling mediated by cyclo-oxygenase-2 (COX2), the target of non-steroidal anti-inflammatory drugs. We inve...

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Detalles Bibliográficos
Autores principales: Keränen, Sara, Suutarinen, Santeri, Mallick, Rahul, Laakkonen, Johanna P., Guo, Diana, Pawlikowska, Ludmila, Jahromi, Behnam Rezai, Rauramaa, Tuomas, Ylä-Herttuala, Seppo, Marchuk, Doug, Krings, Timo, Koivisto, Timo, Lawton, Michael, Radovanovic, Ivan, Kim, Helen, Faughnan, Marie E., Frösen, Juhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Original Article - Vascular Neurosurgery - Arteriovenous malformation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357659/
https://www.ncbi.nlm.nih.gov/pubmed/34185176
http://dx.doi.org/10.1007/s00701-021-04895-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357659/
https://www.ncbi.nlm.nih.gov/pubmed/34185176
http://dx.doi.org/10.1007/s00701-021-04895-z

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