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Nonphosphorylatable PEA15 mutant inhibits epithelial-mesenchymal transition in triple-negative breast cancer partly through the regulation of IL-8 expression

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype that lacks targeted therapies. Patients with TNBC have a very poor prognosis because the disease often metastasizes. New treatment approaches addressing drivers of metastasis and tumor growth are crucial to impro...

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Detalles Bibliográficos
Autores principales: Park, Jihyun, Tacam, Moises J., Chauhan, Gaurav, Cohen, Evan N., Gagliardi, Maria, Iles, Lakesla R., Ueno, Naoto T., Battula, Venkata L., Sohn, Yoo-Kyoung, Wang, Xiaoping, Kim, Hak-Sung, Krishnamurthy, Savitri, Fowlkes, Natalie W., Green, Morgan M., Bartholomeusz, Geoffrey A., Tripathy, Debu, Reuben, James M., Bartholomeusz, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357760/
https://www.ncbi.nlm.nih.gov/pubmed/34241740
http://dx.doi.org/10.1007/s10549-021-06316-2