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Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing

Major depressive disorder (MDD) is the single largest contributor to global disability and up to 20–30% of patients do not respond to at least two antidepressants (treatment-resistant depression, TRD). This study leveraged imputed gene expression in TRD to perform a drug repurposing analysis. Among...

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Detalles Bibliográficos
Autores principales: Fabbri, Chiara, Pain, Oliver, Hagenaars, Saskia P., Lewis, Cathryn M., Serretti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357803/
https://www.ncbi.nlm.nih.gov/pubmed/34158615
http://dx.doi.org/10.1038/s41386-021-01059-6