Structural basis for Ca(2+) activation of the heteromeric PKD1L3/PKD2L1 channel

The heteromeric complex between PKD1L3, a member of the polycystic kidney disease (PKD) protein family, and PKD2L1, also known as TRPP2 or TRPP3, has been a prototype for mechanistic characterization of heterotetrametric TRP-like channels. Here we show that a truncated PKD1L3/PKD2L1 complex with the...

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Detalles Bibliográficos
Autores principales: Su, Qiang, Chen, Mengying, Wang, Yan, Li, Bin, Jing, Dan, Zhan, Xiechao, Yu, Yong, Shi, Yigong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357825/
https://www.ncbi.nlm.nih.gov/pubmed/34381056
http://dx.doi.org/10.1038/s41467-021-25216-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357825/
https://www.ncbi.nlm.nih.gov/pubmed/34381056
http://dx.doi.org/10.1038/s41467-021-25216-z

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