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The switch of DNA states filtering the extrinsic noise in the system of frequency modulation

There is a special node, which the large noise of the upstream element may not always lead to a broad distribution of downstream elements. This node is DNA, with upstream element TF and downstream elements mRNA and proteins. By applying the stochastic simulation algorithm (SSA) on gene circuits insp...

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Detalles Bibliográficos
Autores principales: Lo, Shih-Chiang, You, Chao-Xuan, Chen, Bo-Ren, Hsieh, Ching-Chu, Li, Cheng-En, Shu, Che-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357933/
https://www.ncbi.nlm.nih.gov/pubmed/34381062
http://dx.doi.org/10.1038/s41598-021-95365-0