Predicting Complex Traits and Exposures From Polygenic Scores and Blood and Buccal DNA Methylation Profiles

We examined the performance of methylation scores (MS) and polygenic scores (PGS) for birth weight, BMI, prenatal maternal smoking exposure, and smoking status to assess the extent to which MS could predict these traits and exposures over and above the PGS in a multi-omics prediction model. MS may b...

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Detalles Bibliográficos
Autores principales: Odintsova, Veronika V., Rebattu, Valerie, Hagenbeek, Fiona A., Pool, René, Beck, Jeffrey J., Ehli, Erik A., van Beijsterveldt, Catharina E. M., Ligthart, Lannie, Willemsen, Gonneke, de Geus, Eco J. C., Hottenga, Jouke-Jan, Boomsma, Dorret I., van Dongen, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357987/
https://www.ncbi.nlm.nih.gov/pubmed/34393852
http://dx.doi.org/10.3389/fpsyt.2021.688464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357987/
https://www.ncbi.nlm.nih.gov/pubmed/34393852
http://dx.doi.org/10.3389/fpsyt.2021.688464

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