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Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes

Repeated nicotine exposure leads to sensitization (SST) and enhances self-administration (SA) in rodents. However, the molecular basis of nicotine SST and SA and their biological relevance to the mounting genome-wide association study (GWAS) loci of human addictive behaviors are poorly understood. C...

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Detalles Bibliográficos
Autores principales: Kozlova, Alena, Butler, Robert R., Zhang, Siwei, Ujas, Thomas, Zhang, Hanwen, Steidl, Stephan, Sanders, Alan R., Pang, Zhiping P., Vezina, Paul, Duan, Jubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358005/
https://www.ncbi.nlm.nih.gov/pubmed/34007041
http://dx.doi.org/10.1038/s41386-021-01027-0