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Microtubule associated protein 4 (MAP4) phosphorylation reduces cardiac microvascular density through NLRP3-related pyroptosis

Phosphorylation of MAP4 (p-MAP4) causes cardiac remodeling, with the cardiac microvascular endothelium being considered a vital mediator of this process. In the current study, we investigated the mechanism underlying p-MAP4 influences on cardiac microvascular density. We firstly confirmed elevated M...

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Detalles Bibliográficos
Autores principales: Feng, Yan-hai, Li, Ling-fei, Zhang, Qiong, Zhang, Jun-hui, Huang, Yao, Lv, Yan-ling, Jia, Jie-Zhi, Zhang, Dongxia, Hu, Jiong-Yu, Huang, Yue-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358013/
https://www.ncbi.nlm.nih.gov/pubmed/34381021
http://dx.doi.org/10.1038/s41420-021-00606-w