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Low-dose rapamycin does not impair vascular integrity and tubular regeneration after kidney transplantation in rats

mTOR inhibitors offer advantages after kidney transplantation including antiviral and antitumor activity besides facilitating low calcineurin inhibitor exposure to reduce nephrotoxicity. Concerns about adverse effects due to antiproliferative and antiangiogenic properties have limited their clinical...

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Detalles Bibliográficos
Autores principales: Hoff, Uwe, Markmann, Denise, Nieminen-Kelhä, Melina, Budde, Klemens, Hegner, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358014/
https://www.ncbi.nlm.nih.gov/pubmed/34381142
http://dx.doi.org/10.1038/s41598-021-95790-1