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Low-dose rapamycin does not impair vascular integrity and tubular regeneration after kidney transplantation in rats
mTOR inhibitors offer advantages after kidney transplantation including antiviral and antitumor activity besides facilitating low calcineurin inhibitor exposure to reduce nephrotoxicity. Concerns about adverse effects due to antiproliferative and antiangiogenic properties have limited their clinical...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358014/ https://www.ncbi.nlm.nih.gov/pubmed/34381142 http://dx.doi.org/10.1038/s41598-021-95790-1 |