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Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity

Pyk2 is a Ca(2+)-activated non-receptor tyrosine kinase enriched in the forebrain, especially in pyramidal neurons of the hippocampus. Previous reports suggested its role in hippocampal synaptic plasticity and spatial memory but with contradictory findings possibly due to experimental conditions. He...

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Detalles Bibliográficos
Autores principales: Mastrolia, Vincenzo, al Massadi, Omar, de Pins, Benoit, Girault, Jean-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358019/
https://www.ncbi.nlm.nih.gov/pubmed/34381140
http://dx.doi.org/10.1038/s41598-021-95813-x