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Structural basis of the complementary activity of two ketosynthases in aryl polyene biosynthesis

Aryl polyenes (APE) are one of the most widespread secondary metabolites among gram-negative bacteria. In Acinetobacter baumannii, strains belonging to the virulent global clone 2 (GC2) mostly contain APE biosynthesis genes; its relevance in elevated pathogenicity is of great interest. APE biosynthe...

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Detalles Bibliográficos
Autores principales: Lee, Woo Cheol, Choi, Sungjae, Jang, Ahjin, Yeon, Jiwon, Hwang, Eunha, Kim, Yangmee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358021/
https://www.ncbi.nlm.nih.gov/pubmed/34381152
http://dx.doi.org/10.1038/s41598-021-95890-y