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Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics

Calpain-2 (CAPN2) is a processing enzyme ubiquitously expressed in mammalian tissues whose pleiotropic functions depend on the role played by its cleaved-products. Nuclear interaction networks, crucial for a number of molecular processes, could be modified by CAPN2 activity. However, CAPN2 functions...

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Detalles Bibliográficos
Autores principales: Rodríguez-Fernández, L., Company, S., Zaragozá, R., Viña, J. R., García-Trevijano, E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358030/
https://www.ncbi.nlm.nih.gov/pubmed/34381117
http://dx.doi.org/10.1038/s41598-021-95797-8