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Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics
Calpain-2 (CAPN2) is a processing enzyme ubiquitously expressed in mammalian tissues whose pleiotropic functions depend on the role played by its cleaved-products. Nuclear interaction networks, crucial for a number of molecular processes, could be modified by CAPN2 activity. However, CAPN2 functions...
Autores principales: | Rodríguez-Fernández, L., Company, S., Zaragozá, R., Viña, J. R., García-Trevijano, E. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358030/ https://www.ncbi.nlm.nih.gov/pubmed/34381117 http://dx.doi.org/10.1038/s41598-021-95797-8 |
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