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CTCF is a barrier for 2C-like reprogramming

Totipotent cells have the ability to generate embryonic and extra-embryonic tissues. Interestingly, a rare population of cells with totipotent-like potential, known as 2 cell (2C)-like cells, has been identified within ESC cultures. They arise from ESC and display similar features to those found in...

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Detalles Bibliográficos
Autores principales: Olbrich, Teresa, Vega-Sendino, Maria, Tillo, Desiree, Wu, Wei, Zolnerowich, Nicholas, Pavani, Raphael, Tran, Andy D., Domingo, Catherine N., Franco, Mariajose, Markiewicz-Potoczny, Marta, Pegoraro, Gianluca, FitzGerald, Peter C., Kruhlak, Michael J., Lazzerini-Denchi, Eros, Nora, Elphege P., Nussenzweig, André, Ruiz, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358036/
https://www.ncbi.nlm.nih.gov/pubmed/34381034
http://dx.doi.org/10.1038/s41467-021-25072-x