Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

There is currently a lack of effective drugs to treat people infected with SARS-CoV-2, the cause of the global COVID-19 pandemic. The SARS-CoV-2 Non-structural protein 13 (NSP13) has been identified as a target for anti-virals due to its high sequence conservation and essential role in viral replica...

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Detalles Bibliográficos
Autores principales: Newman, Joseph A., Douangamath, Alice, Yadzani, Setayesh, Yosaatmadja, Yuliana, Aimon, Antony, Brandão-Neto, José, Dunnett, Louise, Gorrie-stone, Tyler, Skyner, Rachael, Fearon, Daren, Schapira, Matthieu, von Delft, Frank, Gileadi, Opher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358061/
https://www.ncbi.nlm.nih.gov/pubmed/34381037
http://dx.doi.org/10.1038/s41467-021-25166-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358061/
https://www.ncbi.nlm.nih.gov/pubmed/34381037
http://dx.doi.org/10.1038/s41467-021-25166-6

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