Clinical Application of TERT Promoter Mutations in Urothelial Carcinoma

Urothelial carcinoma (UC) is a common urological malignancy with a high rate of disease recurrence. Telomerase activity, a hallmark of cancer characterized by overcoming the replicative senescence, is upregulated in over 90% of patients with UC. Somatic mutations in the promoter region of telomerase...

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Detalles Bibliográficos
Autores principales: Hayashi, Yujiro, Fujita, Kazutoshi, Netto, George J., Nonomura, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358429/
https://www.ncbi.nlm.nih.gov/pubmed/34395278
http://dx.doi.org/10.3389/fonc.2021.705440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358429/
https://www.ncbi.nlm.nih.gov/pubmed/34395278
http://dx.doi.org/10.3389/fonc.2021.705440

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