Cinaciguat Prevents Postnatal Closure of Ductus Arteriosus by Vasodilation and Anti-remodeling in Neonatal Rats

Closure of the ductus arteriosus (DA) involves vasoconstriction and vascular remodeling. Cinaciguat, a soluble guanylyl cyclase (sGC) activator, was reported with vasodilatory and anti-remodeling effects on pulmonary hypertensive vessels. However, its effects on DA are not understood. Therefore, we...

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Detalles Bibliográficos
Autores principales: Hung, Yu-Chi, Liu, Yi-Ching, Wu, Bin-Nan, Yeh, Jwu-Lai, Hsu, Jong-Hau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358454/
https://www.ncbi.nlm.nih.gov/pubmed/34393808
http://dx.doi.org/10.3389/fphys.2021.661171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358454/
https://www.ncbi.nlm.nih.gov/pubmed/34393808
http://dx.doi.org/10.3389/fphys.2021.661171

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