Structural basis for the binding of the cancer targeting scorpion toxin, ClTx, to the vascular endothelia growth factor receptor neuropilin-1

Chlorotoxin (ClTx) is a 36-residue disulfide-rich peptide isolated from the venom of the scorpion Leiurus quinquestriatus. This peptide has been shown to selectively bind to brain tumours (gliomas), however, with conflicting reports regarding its direct cellular target. Recently, the vascular endoth...

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Detalles Bibliográficos
Autores principales: Sharma, Gagan, Braga, Carolyne B., Chen, Kai-En, Jia, Xinying, Ramanujam, Venkatraman, Collins, Brett M., Rittner, Roberto, Mobli, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358460/
https://www.ncbi.nlm.nih.gov/pubmed/34401749
http://dx.doi.org/10.1016/j.crstbi.2021.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358460/
https://www.ncbi.nlm.nih.gov/pubmed/34401749
http://dx.doi.org/10.1016/j.crstbi.2021.07.003

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