Cargando…

Effects of hypoxia on DNA hydroxymethylase Tet methylcytosine dioxygenase 2 in a KG-1 human acute myeloid leukemia cell line and its mechanism

Hypoxia is involved in the epigenetic modification of leukemia. As an important DNA hydroxymethylase and a tumor suppressor gene, the expression regulating mechanism of Tet methylcytosine dioxygenase 2 (TET2) remains unclear. The aim of the present study was to explore whether hypoxia and hypoxia-in...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Ping, Lei, Jian, Zou, Li-Xin, Zhou, Gui-Zhen, Peng, Lang, Deng, Qian, Liu, Xiao-Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358611/
https://www.ncbi.nlm.nih.gov/pubmed/34457047
http://dx.doi.org/10.3892/ol.2021.12953