Cargando…
Effects of hypoxia on DNA hydroxymethylase Tet methylcytosine dioxygenase 2 in a KG-1 human acute myeloid leukemia cell line and its mechanism
Hypoxia is involved in the epigenetic modification of leukemia. As an important DNA hydroxymethylase and a tumor suppressor gene, the expression regulating mechanism of Tet methylcytosine dioxygenase 2 (TET2) remains unclear. The aim of the present study was to explore whether hypoxia and hypoxia-in...
Autores principales: | He, Ping, Lei, Jian, Zou, Li-Xin, Zhou, Gui-Zhen, Peng, Lang, Deng, Qian, Liu, Xiao-Liu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358611/ https://www.ncbi.nlm.nih.gov/pubmed/34457047 http://dx.doi.org/10.3892/ol.2021.12953 |
Ejemplares similares
-
Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017) -
Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA
por: Hashimoto, Hideharu, et al.
Publicado: (2013) -
Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli
por: Qin, Wanhai, et al.
Publicado: (2021) -
Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE(−/−) mice
por: Peng, Juan, et al.
Publicado: (2016) -
Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns
por: Adam, Sabrina, et al.
Publicado: (2022)