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The effect of serum starvation on tight junctional proteins and barrier formation in Caco-2 cells

Assessing the ability of pharmaceutics to cross biological barriers and reach the site-of-action requires faithful representation of these barriers in vitro. Difficulties have arisen in replicating in vivo resistance in vitro. This paper investigated serum starvation as a method to increase Caco-2 b...

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Detalles Bibliográficos
Autores principales: Ross, Aisling M., Walsh, Darragh R., Cahalane, Rachel M., Marcar, Lynnette, Mulvihill, John J.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358646/
https://www.ncbi.nlm.nih.gov/pubmed/34401532
http://dx.doi.org/10.1016/j.bbrep.2021.101096