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The effect of serum starvation on tight junctional proteins and barrier formation in Caco-2 cells
Assessing the ability of pharmaceutics to cross biological barriers and reach the site-of-action requires faithful representation of these barriers in vitro. Difficulties have arisen in replicating in vivo resistance in vitro. This paper investigated serum starvation as a method to increase Caco-2 b...
Autores principales: | Ross, Aisling M., Walsh, Darragh R., Cahalane, Rachel M., Marcar, Lynnette, Mulvihill, John J.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358646/ https://www.ncbi.nlm.nih.gov/pubmed/34401532 http://dx.doi.org/10.1016/j.bbrep.2021.101096 |
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