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DNA Methylation Signature of Epileptic Encephalopathy-Related Pathogenic Genes Encoding Ion Channels in Temporal Lobe Epilepsy

Epilepsy is characterized by highly abnormal synchronous discharge of brain neurons, and ion channels are fundamental in the generation and modulation of neural excitability. Considering that abnormal methylation can either activate or repress genes, this study was designed to explore the DNA methyl...

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Detalles Bibliográficos
Autores principales: Tao, Hua, Chen, Zengqiang, Wu, Jianhao, Chen, Jun, Chen, Yusen, Fu, Jiawu, Sun, Chaowen, Zhou, Haihong, Zhong, Wangtao, Zhou, Xu, Li, Keshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358672/
https://www.ncbi.nlm.nih.gov/pubmed/34393975
http://dx.doi.org/10.3389/fneur.2021.692412