The unique Phe–His dyad of 2-ketopropyl coenzyme M oxidoreductase/carboxylase selectively promotes carboxylation and S–C bond cleavage

The 2-ketopropyl-coenzyme M oxidoreductase/carboxylase (2-KPCC) enzyme is the only member of the disulfide oxidoreductase (DSOR) family of enzymes, which are important for reductively cleaving S–S bonds, to have carboxylation activity. 2-KPCC catalyzes the conversion of 2-ketopropyl-coenzyme M to ac...

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Detalles Bibliográficos
Autores principales: Prussia, Gregory A., Shisler, Krista A., Zadvornyy, Oleg A., Streit, Bennett R., DuBois, Jennifer L., Peters, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358701/
https://www.ncbi.nlm.nih.gov/pubmed/34265301
http://dx.doi.org/10.1016/j.jbc.2021.100961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358701/
https://www.ncbi.nlm.nih.gov/pubmed/34265301
http://dx.doi.org/10.1016/j.jbc.2021.100961

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