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Prolactin enhances T regulatory cell promotion of breast cancer through the long form prolactin receptor

Previous work has shown systemic knockdown of the long form prolactin receptor (LFPRLR) in vivo markedly reduced metastasis in mouse models of breast cancer, but whether this translated to prolonged survival was unknown. Here we show that LFPRLR knockdown in the highly metastatic, immunocompetent 4T...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Hui Ethan, Ghosh, Mrinal, Rivera, Lorena, Lin, Samuel, Kumar, Anil, Swaminathan, Srividya, Lorenson, Mary Y., Walker, Ameae M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358703/
https://www.ncbi.nlm.nih.gov/pubmed/34375938
http://dx.doi.org/10.1016/j.tranon.2021.101195