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KDM4C contributes to cytarabine resistance in acute myeloid leukemia via regulating the miR-328-3p/CCND2 axis through MALAT1

AIMS: Acute myeloid leukemia (AML) is an aggressive hematologic neoplasm, in which relapse due to drug resistance is the main cause for treatment failure and the disease progression. In this study, we aimed to investigate the molecular mechanism of KDM4C-dependent MALAT1/miR-328-3p/CCND2 axis in cyt...

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Detalles Bibliográficos
Autores principales: Xue, Lu, Li, Chunhuai, Ren, Jin, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358730/
https://www.ncbi.nlm.nih.gov/pubmed/34394903
http://dx.doi.org/10.1177/2040622321997259