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Cancer Cells Can Exhibit a Sparing FLASH Effect at Low Doses Under Normoxic In Vitro-Conditions

BACKGROUND: Irradiation with ultra-high dose rate (FLASH) has been shown to spare normal tissue without hampering tumor control in several in vivo studies. Few cell lines have been investigated in vitro, and previous results are inconsistent. Assuming that oxygen depletion accounts for the FLASH spa...

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Detalles Bibliográficos
Autores principales: Adrian, Gabriel, Konradsson, Elise, Beyer, Sarah, Wittrup, Anders, Butterworth, Karl T., McMahon, Stephen J., Ghita, Mihaela, Petersson, Kristoffer, Ceberg, Crister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358772/
https://www.ncbi.nlm.nih.gov/pubmed/34395253
http://dx.doi.org/10.3389/fonc.2021.686142