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Involvement and Targeted Intervention of Mortalin-Regulated Proteome Phosphorylated-Modification in Hepatocellular Carcinoma

OBJECTIVES: To reveal the mechanisms of the effects of mortalin in hepatocellular carcinoma (HCC) and to identify potential novel chemical inhibitors of mortalin. MATERIALS AND METHODS: For the experiments, three HCC cell lines (HepG2 cells, Hep3B cells, and sorafenib-resistant HuH7 cells) and xenog...

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Detalles Bibliográficos
Autores principales: Yang, Ye, Jin, Ming, Dai, Yi, Shan, Wenqi, Chen, Shuai, Cai, Rong, Yang, Haojun, Tang, Liming, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358780/
https://www.ncbi.nlm.nih.gov/pubmed/34395254
http://dx.doi.org/10.3389/fonc.2021.687871