Geranylgeranylacetone promotes human osteosarcoma cell apoptosis by inducing the degradation of PRMT1 through the E3 ubiquitin ligase CHIP

Geranylgeranylacetone (GGA), an inducer of heat shock proteins, exerts anticancer activity in some tumours. However, the effect of GGA on human osteosarcoma (OS) has not been reported. This work is designed to evaluate the effect of GGA on the proliferation and apoptosis of human OS cells and to exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Lucen, Liao, Jia, Liu, Jianghuan, Wei, Qingzhu, Wang, Yiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358878/
https://www.ncbi.nlm.nih.gov/pubmed/34155784
http://dx.doi.org/10.1111/jcmm.16725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358878/
https://www.ncbi.nlm.nih.gov/pubmed/34155784
http://dx.doi.org/10.1111/jcmm.16725

Ejemplares similares