Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF‐β/Smad signalling in type 2 diabetic rats

Diabetic cardiomyopathy (DCM) is one of the leading causes of heart failure in patients with diabetes mellitus, with limited effective treatments. The cardioprotective effects of sodium‐glucose cotransporter 2(SGLT2) inhibitors have been supported by amounts of clinical trials, which largely fills t...

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Detalles Bibliográficos
Autores principales: Tian, Jingjing, Zhang, Mingjun, Suo, Mengying, Liu, Dian, Wang, Xuyang, Liu, Ming, Pan, Jinyu, Jin, Tao, An, Fengshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358881/
https://www.ncbi.nlm.nih.gov/pubmed/34169635
http://dx.doi.org/10.1111/jcmm.16601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358881/
https://www.ncbi.nlm.nih.gov/pubmed/34169635
http://dx.doi.org/10.1111/jcmm.16601

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