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MiR‐132 down‐regulates high glucose‐induced β‐dystroglycan degradation through Matrix Metalloproteinases‐9 up‐regulation in primary neurons

Cognitive dysfunction is one of the complications of diabetes. Unfortunately, there is no effective methods to block its progression currently. One of the pathophysiological mechanisms is synaptic protein damage and neuronal signal disruption because of glucose metabolism disorder. Dystroglycan prot...

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Detalles Bibliográficos
Autores principales: Dou, Yunxiao, Tan, Yan, Yu, Tongya, Ma, Xiaoye, Zhou, Yuchen, Zhao, Yichen, Zhao, Yanxin, Liu, Xueyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358889/
https://www.ncbi.nlm.nih.gov/pubmed/34160889
http://dx.doi.org/10.1111/jcmm.16669