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Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post‐ischaemic inflammatory response

Phosphorylcholine is a pro‐inflammatory epitope exposed on apoptotic cells, and phosphorylcholine monoclonal immunoglobulin (Ig)G antibodies (PC‐mAb) have anti‐inflammatory properties. In this study, we hypothesize that PC‐mAb treatment reduces adverse cardiac remodelling and infarct size (IS) follo...

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Detalles Bibliográficos
Autores principales: Pluijmert, Niek J., de Jong, Rob C. M., de Vries, Margreet R., Pettersson, Knut, Atsma, Douwe E., Jukema, J. Wouter, Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358891/
https://www.ncbi.nlm.nih.gov/pubmed/34190404
http://dx.doi.org/10.1111/jcmm.16662