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Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2

PURPOSE: Rapid antigen-detecting tests (Ag-RDTs) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can transform pandemic control. Thus far, sensitivity (≤ 85%) of lateral-flow assays has limited scale-up. Conceivably, microfluidic immunofluorescence Ag-RDTs could increase sensitivity...

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Detalles Bibliográficos
Autores principales: Krüger, Lisa J., Klein, Julian A. F., Tobian, Frank, Gaeddert, Mary, Lainati, Federica, Klemm, Sarah, Schnitzler, Paul, Bartenschlager, Ralf, Cerikan, Berati, Neufeldt, Christopher J., Nikolai, Olga, Lindner, Andreas K., Mockenhaupt, Frank P., Seybold, Joachim, Jones, Terry C., Corman, Victor M., Pollock, Nira R., Knorr, Britta, Welker, Andreas, de Vos, Margaretha, Sacks, Jilian A., Denkinger, Claudia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358901/
https://www.ncbi.nlm.nih.gov/pubmed/34383260
http://dx.doi.org/10.1007/s15010-021-01681-y