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Brahma-related gene-1 promotes tubular senescence and renal fibrosis through Wnt/β-catenin/autophagy axis

Although accelerated cellular senescence is closely related to the progression of chronic kidney disease (CKD) and renal fibrosis, the underlying mechanisms remain largely unknown. Here, we reported that tubular aberrant expression of Brahma-related gene 1 (BRG1), an enzymatic subunit of the SWItch/...

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Detalles Bibliográficos
Autores principales: Gong, Wangqiu, Luo, Congwei, Peng, Fenfen, Xiao, Jing, Zeng, Yiqun, Yin, Bohui, Chen, Xiaowen, Li, Shuting, He, Xiaoyang, Liu, Yanxia, Cao, Huihui, Xu, Jiangping, Long, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358963/
https://www.ncbi.nlm.nih.gov/pubmed/34318888
http://dx.doi.org/10.1042/CS20210447