Cargando…

Brahma-related gene-1 promotes tubular senescence and renal fibrosis through Wnt/β-catenin/autophagy axis

Although accelerated cellular senescence is closely related to the progression of chronic kidney disease (CKD) and renal fibrosis, the underlying mechanisms remain largely unknown. Here, we reported that tubular aberrant expression of Brahma-related gene 1 (BRG1), an enzymatic subunit of the SWItch/...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Wangqiu, Luo, Congwei, Peng, Fenfen, Xiao, Jing, Zeng, Yiqun, Yin, Bohui, Chen, Xiaowen, Li, Shuting, He, Xiaoyang, Liu, Yanxia, Cao, Huihui, Xu, Jiangping, Long, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Gastrointestinal, Renal & Hepatic Systems
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358963/ https://www.ncbi.nlm.nih.gov/pubmed/34318888 http://dx.doi.org/10.1042/CS20210447

Ejemplares similares

Optimal blood pressure for the minimum all-cause mortality in Chinese ESRD patients on maintenance hemodialysis
por: Wang, Tao, et al.
Publicado: (2020)

Small intestine resection increases oxalate and citrate transporter expression and calcium oxalate crystal formation in rat hyperoxaluric kidneys
por: Tseng, Yi-Shiou, et al.
Publicado: (2020)

Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expression
por: Rishi, Gautam, et al.
Publicado: (2020)

Evaluation of carbon tetrachloride fraction of Actinodaphne angustifolia Nees (Lauraceae) leaf extract for antioxidant, cytotoxic, thrombolytic and antidiarrheal properties
por: Uddin, Mohammad Najim, et al.
Publicado: (2020)

Proton pump inhibitor use and mortality in patients with cirrhosis: a meta-analysis of cohort studies
por: Wu, Xiaoli, et al.
Publicado: (2020)

Emodin protects against intestinal and lung injury induced by acute intestinal injury by modulating SP-A and TLR4/NF-κB pathway
por: Qian, Jingli, et al.
Publicado: (2020)

Emodin ameliorates renal injury in BXSB mice by modulating TNF-α/ICAM-1
por: Yuan, Xinlu, et al.
Publicado: (2020)

Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery
por: Tang, Chaoliang, et al.
Publicado: (2020)

RCAN1.4 mediates high glucose-induced matrix production by stimulating mitochondrial fission in mesangial cells
por: Chen, Hong-Min, et al.
Publicado: (2020)

MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline
por: Yao, Weifeng, et al.
Publicado: (2020)

Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease
por: Hou, Wei, et al.
Publicado: (2020)

Renal damage after liver transplantation
por: Feldkamp, Thorsten, et al.
Publicado: (2020)

Cajanonic acid A regulates the ratio of Th17/Treg via inhibition of expression of IL-6 and TGF-β in insulin-resistant HepG2 cells
por: Gong, Yanfeng, et al.
Publicado: (2019)

Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia
por: Fu, Ming, et al.
Publicado: (2021)

NPHS2 gene polymorphism aggravates renal damage caused by focal segmental glomerulosclerosis with COL4A3 mutation
por: Sun, Liping, et al.
Publicado: (2021)

Association of α-fetoprotein levels with liver stiffness measurement in outpatients with chronic hepatitis B
por: Wang, Juan, et al.
Publicado: (2021)

Lactobacillus rhamnosus GG soluble mediators ameliorate early life stress-induced visceral hypersensitivity and changes in spinal cord gene expression
por: McVey Neufeld, Karen-Anne, et al.
Publicado: (2020)

Intestinal congestion and reperfusion injury: damage caused to the intestinal tract and distal organs
por: Chen, Yajing, et al.
Publicado: (2021)

The positive rates of hepatitis B surface antibody in youth after booster vaccination: a 4-year follow-up study with large sample
por: Zhu, Xia, et al.
Publicado: (2021)

Gualou Xiebai Banxia decoction ameliorates Poloxamer 407-induced hyperlipidemia
por: Luo, Mingzhu, et al.
Publicado: (2021)

Jian-Pi-Yi-Shen formula enhances perindopril inhibition of chronic kidney disease progression by activation of SIRT3, modulation of mitochondrial dynamics, and antioxidant effects
por: Liu, Xinhui, et al.
Publicado: (2021)

DUSP12 acts as a novel endogenous protective signal against hepatic ischemia–reperfusion damage by inhibiting ASK1 pathway
por: Boldorini, Renzo, et al.
Publicado: (2021)

Role of fatty acid transport protein 4 in metabolic tissues: insights into obesity and fatty liver disease
por: Li, Huili, et al.
Publicado: (2022)

The antioxidant and anti-inflammatory effects of Eremina desertorum snail mucin on experimentally induced intestinal inflammation and testicular damage
por: Ibrahim, Amina M., et al.
Publicado: (2022)

The pathogenesis of gut microbiota in hepatic encephalopathy by the gut–liver–brain axis
por: Zhu, Ruirui, et al.
Publicado: (2023)

Pharmacokinetic studies of hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex and ameliorated DSS-induced colitis in mice
por: Su, Jianqing, et al.
Publicado: (2023)

HOTAIR as a diagnostic and prognostic biomarker of gastrointestinal cancers: an updated meta-analysis and bioinformatics analysis based on TCGA data
por: Yang, Jinyou, et al.
Publicado: (2023)

Melatonin targets ferroptosis through bimodal alteration of redox environment and cellular pathways in NAFLD model
por: Saha, Moumita, et al.
Publicado: (2023)

Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney
por: McArdle, Zoe, et al.
Publicado: (2023)

Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70-deficient mice with a human-like bile acid composition
por: Sjöland, Wilhelm, et al.
Publicado: (2023)

Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition
por: Verkade, Esther, et al.
Publicado: (2023)

Brahma-related gene 1 acts as a profibrotic mediator and targeting it by micheliolide ameliorates peritoneal fibrosis
por: Li, Shuting, et al.
Publicado: (2023)

Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea
por: Griggs, David W., et al.
Publicado: (2016)

Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs
por: Clay, Emlyn, et al.
Publicado: (2016)

Effects of Antihypertensive Agents on Intestinal Contractility in the Spontaneously Hypertensive Rat: Angiotensin Receptor System Downregulation by Losartan
por: Patten, Glen Stephen, et al.
Publicado: (2017)

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
por: Floettmann, Eike, et al.
Publicado: (2017)

A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
por: Kuo, Joseph, et al.
Publicado: (2019)

8-Aminoinosine and 8-Aminohypoxanthine Inhibit Purine Nucleoside Phosphorylase and Exert Diuretic and Natriuretic Activity
por: Jackson, Edwin K., et al.
Publicado: (2022)

Dietary sodium induces a redistribution of the tubular metabolic workload
por: Udwan, Khalil, et al.
Publicado: (2017)

Safety of hepatitis E vaccination for pregnancy: a post-hoc analysis of a randomized, double-blind, controlled phase 3 clinical trial
por: Zhong, Guohua, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0lucket8nuptqva53efipl7rcp