Identification of active small-molecule modulators targeting the novel immune checkpoint VISTA

BACKGROUND: Cancer immunotherapy has gained increasing popularity as a novel approach to treat cancer. A member of the B7 family, V-domain immunoglobulin suppressor of T-cell activation (VISTA) is a novel immune checkpoint that regulates a broad spectrum of immune responses. VISTA is an acidic pH-se...

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Detalles Bibliográficos
Autores principales: Li, Ting-ting, Jiang, Jing-wei, Qie, Chen-xin, Xuan, Chun-xiao, Hu, Xin-lei, Liu, Wan-mei, Chen, Wen-ting, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359099/
https://www.ncbi.nlm.nih.gov/pubmed/34380434
http://dx.doi.org/10.1186/s12865-021-00446-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359099/
https://www.ncbi.nlm.nih.gov/pubmed/34380434
http://dx.doi.org/10.1186/s12865-021-00446-4

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