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Novel Machaeriol Analogues as Modulators of Cannabinoid Receptors: Structure–Activity Relationships of (+)-Hexahydrocannabinoids and Their Isoform Selectivities

[Image: see text] Machaeriols are an important class of compounds that structurally resemble tetrahydrocannabinol (Δ(9)-THC), with the major differences being inverted stereochemistry at the ring junction as [6aR, 10aR] and an additional stereocenter at the C9 position of the A-ring due to saturatio...

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Detalles Bibliográficos
Autores principales: Haider, Saqlain, Pandey, Pankaj, Reddy, Chada Raji, Lambert, Janet A., Chittiboyina, Amar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359128/
https://www.ncbi.nlm.nih.gov/pubmed/34395989
http://dx.doi.org/10.1021/acsomega.1c02413