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Novel Machaeriol Analogues as Modulators of Cannabinoid Receptors: Structure–Activity Relationships of (+)-Hexahydrocannabinoids and Their Isoform Selectivities
[Image: see text] Machaeriols are an important class of compounds that structurally resemble tetrahydrocannabinol (Δ(9)-THC), with the major differences being inverted stereochemistry at the ring junction as [6aR, 10aR] and an additional stereocenter at the C9 position of the A-ring due to saturatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359128/ https://www.ncbi.nlm.nih.gov/pubmed/34395989 http://dx.doi.org/10.1021/acsomega.1c02413 |