Cargando…

Asymmetric Chemoenzymatic One-Pot Synthesis of α-Hydroxy Half-Esters

[Image: see text] A new chemoenzymatic one-pot strategy has been developed for the synthesis of α-hydroxy half-esters containing consecutive quaternary and tertiary stereocenters using asymmetric cascade catalysis. In this study, an asymmetric Ca(2+)-catalyzed [2,3]-Wittig rearrangement reaction was...

Descripción completa

Detalles Bibliográficos
Autores principales: Murre, Aleksandra, Erkman, Kristin, Järving, Ivar, Kanger, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359131/
https://www.ncbi.nlm.nih.gov/pubmed/34396014
http://dx.doi.org/10.1021/acsomega.1c02973