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Trinuclear Calcium Site in the C2 Domain of PKCα/γ Is Prone to Lithium Attack

[Image: see text] Lithium (Li(+)) is the first-line therapy for bipolar disorder and a candidate drug for various diseases such as amyotrophic lateral sclerosis, multiple sclerosis, and stroke. Despite being the captivating subject of many studies, the mechanism of lithium’s therapeutic action remai...

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Detalles Bibliográficos
Autores principales: Grauffel, Cédric, Weng, Wei-Hsiang, Dudev, Todor, Lim, Carmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359144/
https://www.ncbi.nlm.nih.gov/pubmed/34396011
http://dx.doi.org/10.1021/acsomega.1c02882