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Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium

DNA gyrase is an essential type II topoisomerase that is composed of two subunits, GyrA and GyrB, and has an A(2)B(2) structure. Although the A and B subunits are required in equal proportions to form DNA gyrase, the gyrA and gyrB genes that encode them in Salmonella (and in many other bacteria) are...

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Detalles Bibliográficos
Autores principales: Pozdeev, German, Mogre, Aalap, Dorman, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359277/
https://www.ncbi.nlm.nih.gov/pubmed/33539568
http://dx.doi.org/10.1111/mmi.14689