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Comparison of Steroidogenic Exposure Following the Administration of Repository Corticotropin Injection With a Synthetic ACTH(1‐24) Depot and Methylprednisolone in Healthy Subjects

The pharmacokinetics (PK) and pharmacodynamics (PD) of clinically relevant doses of repository corticotropin injection (Acthar Gel) and synthetic ACTH(1‐24) depot have not been fully characterized. We compared the steroidogenic exposure of repository corticotropin injection and synthetic ACTH(1‐24)...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofeng, Pham, Loan, Poola, Nagaraju, Brooks, Leah R., Due, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359281/
https://www.ncbi.nlm.nih.gov/pubmed/33369276
http://dx.doi.org/10.1002/cpdd.894