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Constructing a representative in‐silico population for paediatric simulations: Application to HIV‐positive African children
AIMS: Simulations are an essential tool for investigating scenarios in pharmacokinetics‐pharmacodynamics. The models used during simulation often include the effect of highly correlated covariates such as weight, height and sex, and for children also age, which complicates the construction of an in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359354/ https://www.ncbi.nlm.nih.gov/pubmed/33294979 http://dx.doi.org/10.1111/bcp.14694 |