Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach

BACKGROUND: It is not enough to optimize proteomics assays. It is critical those assays are robust to operating conditions. Without robust assays, proteomic biomarkers are unlikely to translate readily into the clinic. This study outlines a structured approach to the identification of a robust opera...

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Detalles Bibliográficos
Autores principales: Serrano-Blesa, Edith, Porter, Andrew, Lendrem, Dennis W., Pitzalis, Costantino, Barton, Anne, Treumann, Achim, Isaacs, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359389/
https://www.ncbi.nlm.nih.gov/pubmed/34384350
http://dx.doi.org/10.1186/s12014-021-09323-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359389/
https://www.ncbi.nlm.nih.gov/pubmed/34384350
http://dx.doi.org/10.1186/s12014-021-09323-z

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