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Inducing regulated necrosis and shifting macrophage polarization with anti‐EMMPRIN antibody (161‐pAb) and complement factors

Treatment of solid tumors is often hindered by an immunosuppressive tumor microenvironment (TME) that prevents effector immune cells from eradicating tumor cells and promotes tumor progression, angiogenesis, and metastasis. Therefore, targeting components of the TME to restore the ability of immune...

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Detalles Bibliográficos
Autores principales: Hijaze, Nizar, Ledersnaider, Max, Simanovich, Elina, Kassem, Sameer, Rahat, Michal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359428/
https://www.ncbi.nlm.nih.gov/pubmed/33205451
http://dx.doi.org/10.1002/JLB.3A0520-333R