Enantiomer‐specific pharmacokinetics of D,L‐3‐hydroxybutyrate: Implications for the treatment of multiple acyl‐CoA dehydrogenase deficiency

D,L‐3‐hydroxybutyrate (D,L‐3‐HB, a ketone body) treatment has been described in several inborn errors of metabolism, including multiple acyl‐CoA dehydrogenase deficiency (MADD; glutaric aciduria type II). We aimed to improve the understanding of enantiomer‐specific pharmacokinetics of D,L‐3‐HB. Usin...

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Detalles Bibliográficos
Autores principales: van Rijt, Willemijn J., Van Hove, Johan L. K., Vaz, Frédéric M., Havinga, Rick, Allersma, Derk P., Zijp, Tanja R., Bedoyan, Jirair K., Heiner‐Fokkema, M. R., Reijngoud, Dirk‐Jan, Geraghty, Michael T., Wanders, Ronald J. A., Oosterveer, Maaike H., Derks, Terry G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359440/
https://www.ncbi.nlm.nih.gov/pubmed/33543789
http://dx.doi.org/10.1002/jimd.12365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359440/
https://www.ncbi.nlm.nih.gov/pubmed/33543789
http://dx.doi.org/10.1002/jimd.12365

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